Anti-Globo H mAb for Cancer Therapy (抗醣抗原Globo H單株抗體在癌症治療的應用)

 

Technology/ Title

Anti-Globo H mAb for Cancer Therapy

Technology Type

□Biotechnology

□Device/Diagnostics

Pharmaceutical

□Others:_____________-

Contact Person

 

Name: Joseph Liu

Title: Project Manager

Telephone(work):

+886-02-7700-3800 ext. 5237

Mobile:

Email: joseph.liu@dcb.org.tw

Link

http://

 

 

Technology Description

 

Summary of Invention:

Globo H is one of the surface markers in various cancer cells, including breast cancer, ovarian cancer, pancreatic cancer, prostate cancer , thyroid cancer, and liver cancer. The anti-Globo H monoclonal antibody targets Globo H expressing cancer cells and eradicates the cancer through ADCC and CDC.

 

Advantages when compared to the existing technologies:

  • In contrast to the anti-Her2 mAb (i.e. Trastuzumab) which targets 20% of breast cancer patients, the anti-Globo H mAb will cover more than 60% of total breast cancer patients.
  • With the specificity to Globo H, the anti-Globo H mAb enhances the antibody-mediated tumor cell eradication by ADCC and CDC.

Intellectual Property

US, PCT, TW patents filed

Key Publications

 

 

Business Opportunity

Antibody-mediated cancer therapy